Robin Mesnage

Health benefits of a five-day at-home modified fasting program: a randomised controlled trial.

Grundler F, Ducarmon QR, Holley A, Knufinke M, Strathmeyer S, Heelemann S, Geyer R, Tellez BM, MacArthur MR, Zeller G, Wilhelmi de Toledo F, Mesnage R (2024)

MedRxiv 2024.11.01.24316348

DOI: 10.1101/2024.11.01.24316348

Myths and Facts in the Debates on the Effects of Long-Term Fasting.

Mesnage R (2024)

Insights Into the Therapeutic Applications of Fasting. IntechOpen.

DOI: 10.5772/intechopen.1007577

Impact of long-term fasting on breath volatile sulphur compounds, inflammatory markers and saliva microbiota composition.

Loume A, Grundler F, Wilhelmi de Toledo F, Giannopoulou C, Mesnage R (2024)

Oral Health and Preventive Dentistry. Oct 24:22:525-540.

DOI: 10.3290/j.ohpd.b5795653

Enhanced Labeling to Promote Consumption of Nutrient Dense Foods and Healthier Diets

Benbrook C, Mesnage R

Foods 2024, 13(21), 3377;

DOI 10.3390/foods13213377

HDL cholesterol efflux capacity and cholesterol loading capacity in long-term fasting: evidence from a prospective, single-arm interventional study in healthy individuals

Grundler F, Palumbo M, Adorni MP, Zimetti F, Papotti B, Plonne D, Holley A, Mesnage R, Ruscica M, Wilhelmi de Toledo F. (2024)

Atherosclerosis. Available online 6 August 2024, 118548

DOI 10.1016/j.atherosclerosis.2024.118548

Long-term fasting remodels gut microbial metabolism and host metabolism

Ducarmon QR, Grundler F, Giannopoulou C, Loumé A, Karcher N, Larralde M, Romano S, MacArthur MR, Mitchell SJ, Wilhelmi de Toledo F, Zeller G, Mesnage R (2024)

bioRxiv 2024.04.19.590209

DOI 10.1101/2024.04.19.590209v1

Long-Term Fasting-Induced Ketosis in 1610 Subjects: Metabolic Regulation and Safety

Grundler F, Mesnage R, Ruppert PMM, Kouretas D, Wilhelmi de Toledo F. (2024)

Nutrients. 2024 Jun 13;16(12):1849

DOI 10.3390/nu16121849

Long-term Fasting Promotes Reversible Cardiometabolic Switching: An MR Spectroscopy Study

Rapacchi S, Roussel T, Sourdon J, Ratiney H, Petrusca-Perisanu L, Grundler F, Mesnage R, Wilhelmi De Toledo F, Croisille P, Viallon M. (2024)

Journal of Cardiovascular Magnetic Resonance, 2024, vol. 26.

DOI 10.1016/j.jocmr.2024.100837

The Conflict between Regulatory Agencies over the 20,000-Fold Lowering of the Tolerable Daily Intake (TDI) for Bisphenol A (BPA) by the European Food Safety Authority (EFSA)

Vom Saal FS, Antoniou M, Belcher SM, Bergman A, Bhandari RK, Birnbaum LS, Cohen A, Collins TJ, Demeneix B, Fine AM, Flaws JA, Gayrard V, Goodson WH 3rd, Gore AC, Heindel JJ, Hunt PA, Iguchi T, Kassotis CD, Kortenkamp A, Mesnage R, Muncke J, Myers JP, Nadal A, Newbold RR, Padmanabhan V, Palanza P, Palma Z, Parmigiani S, Patrick L, Prins GS, Rosenfeld CS, Skakkebaek NE, Sonnenschein C, Soto AM, Swan SH, Taylor JA, Toutain PL, von Hippel FA, Welshons WV, Zalko D, Zoeller RT (2024)

Environ Health Perspect. 2024 Apr;132(4):45001

DOI 10.1289/EHP13812

Ribosomal DNA copy number is associated with body mass in humans and other mammals

Law PP, Rodriguez-Algarra F, Asenius F, Gregori M, Seaborne R, Yildizoglu S, Miller J, Mesnage R, Antoniou MN, Li W, Tan Q, Hillman SL, Rakyan V, Williams DJ, Holland ML (2023)

Nature Communications volume 15, Article number: 5006

DOI 10.1038/s41467-024-49397-5

World’s longest medically documented repeated fasting history in a 92 years old man who fasted 21 days yearly for 45 years: a case report

Wilhelmi de Toledo F, Grundler F, Mesnage R (2024)

Journal of Integrative and Complementary Medicine

DOI 10.1089/jicm.2023.0352

(Poly)phenol-related gut metabotypes and human health: an update

Hu J, Mesnage R, Tuohy K, Heiss C, Rodriguez-Mateos A (2024)

Food and Function

DOI 10.1039/D3FO04338J

Aquatic ecotoxicity of glyphosate, its formulations, and co-formulants: evidence from 2010 to 2023

Klátyik S, Simon G, Oláh M, Takács E,Mesnage R, Antoniou MN, Zaller J, Székács A (2024)

Environmental Sciences Europe 36:22

DOI 10.1186/s12302-024-00849-1

Improvements during long-term fasting in patients with long COVID: a case series and literature review

Grundler F, Mesnage R, Cerrada A, Wilhelmi de Toledo F (2023)

Front. Nutr. Sec. Clinical Nutrition. Volume 10 - 2023

DOI 10.3389/fnut.2023.1195270

Remodelling of the intestinal ecosystem during caloric restriction and fasting

Ducarmon Q, Grundler F, Le Maho Y, Wilhelmi de Toledo F, Zeller G, Habold C, Mesnage R (2023)

Trends in Microbiology

DOI 10.1016/j.tim.2023.02.009

Wild Blueberry (Poly)phenols can Improve Vascular Function And Cognitive Performance In Healthy Older Males And Females: A Double-Blind Randomized Controlled Trial

Wood E, Hein S, Mesnage R, Fernandes F, Abhayaratne N, Xu Y, Zhang Z, Bell L, Williams C, Rodriguez-Mateos A (2023)

The American Journal of Clinical Nutrition

DOI 10.1016/j.ajcnut.2023.03.017

Effect of perinatal exposure to glyphosate and its mixture with 2,4-D and dicamba on rat dam kidney and thyroid function and offspring's health

Docea A, Cirstea AE, Cercelaru L, Drocas AI, Dinca V, Mesnage R, Marginean C, Radu A, Popa DG, Rogoveanu O, Mitrut R, Antoniou MN, Tsatsakis A, Hernández AF, Calina D (2023)

Environmental Research. Available online 17 August 2023, 116908

DOI 10.1016/j.envres.2023.116908

No impacts of glyphosate or Crithidia bombi, or their combination, on the bumblebee microbiome

Straw EA, Mesnage R, Brown MF, Antoniou MN (2023)

Scientific Reports

DOI 10.1038/s41598-023-35304-3

Terrestrial ecotoxicity of glyphosate, its formulations, and co-formulants: evidence from 2010–2023

Klátyik S, Simon G, Oláh M, Mesnage R, et al. (2023)

Environ Sci Eur 35, 51

DOI 10.1186/s12302-023-00758-9

Evaluation of perinatal exposure of glyphosate and its mixture with 2,4-D and dicamba οn liver redox status in Wistar rats

Nechalioti P, Karampatzakis T, Mesnage R, Antoniou MN, Ibragim M, Tsatsakis A, Docea A, Nepka C, Kouretas D (2023)

Environmental Research 228: 115906

DOI 10.1016/j.envres.2023.115906

Comparison of transcriptome alterations induced by pendimethalin or its commercial formulation Stomp Aqua in human MCF-7, MCF-10A and MCF-12A mammary epithelial cells

Mesnage R, Omriouate H, Antoniou MN (2023)

BMC Research Notes 16, 62

DOI 10.1186/s13104-023-06327-w

Leveraging the self-healing abilities of our body to promote healthy longevity

Mesnage R, Grundler F, Wilhelmi de Toledo F (2023)

Public Health Toxicology 3(1)

DOI 10.18332/pht/161464

The GlyphoMix protocol: Multiorgan changes caused by prenatal exposure to glyphosate or its mixture with 2,4-D and dicamba in rats

Mesnage R, Nepka C, Ferguson S, Kouretas D, Stivaktakis PD, Calina D, Tsatsakis A, Antoniou MN, Docea A (2023)

Public Health Toxicology 3(1):7

DOI 10.18332/pht/161987

Effect of Combination of Lactobacillus acidophilus (Probiotic) with Vitamin K3 and Vitamin E on Escherichia coli and Staphylococcus aureus: in vitro pathogen model

Celebi O, Taghizadehghalehjoughi A, Celebi D, Mesnage R, Golokhvas KS, Arsene AL, Spandidos DA, Tsatsakis A (2023)

Molecular Medicine Reports 27: 119

DOI 10.3892/mmr.2023.13006

Low-Dose Effects of Environmental Chemicals: Bisphenol A as a Case Study

Powell C, Mesnage R, Antoniou MN, Vandenberg LN (2023)

Reference Module in Biomedical Sciences. Encyclopedia of Toxicology, 4th Edition

DOI 10.1016/B978-0-12-824315-2.00762-4

Genotoxicity Assays Published since 2016 Shed New Light on the Oncogenic Potential of Glyphosate-Based Herbicides

Benbrook C, Mesnage R, Sawyer W (2023)

Agrochemicals 2(1):47-68

DOI 10.3390/agrochemicals2010005

Reproductive Effects of S. boulardii on Sub-Chronic Acetamiprid and Imidacloprid Toxicity in Male Rats

Sevim Ç, Akpınar E, Aksu EH, Ömür AD, Yıldırım S, Kara M, Bolat İ, Tsatsakis A, Mesnage R, Golokhvast KS, Uzunçakmak SK, Ersoylu RN (2023)

Toxics 11(2):170

DOI 10.3390/toxics11020170

Use of the concept “environmentally relevant level” in linking the results of pesticide toxicity studies to public health outcomes

Mesnage R, Benbrook C (2023)

All Life 16:1

DOI 10.1080/26895293.2023.2167872

Cytotoxicity mechanisms of eight major herbicide active ingredients in comparison to their commercial formulations

Ferguson S, Mesnage R, Antoniou M (2022)

Toxics 10(11), 711

DOI 2305-6304/10/11/711

Long-term fasting: multi-system adaptations in humans (GENESIS) study - a single-arm interventional trial

Grundler F, Viallon M, Mesnage R, Ruscica M, von Schacky C, Madeo F, Hofer S, Mitchell S, Croisille P, Wilhelmi de Toledo F (2022)

Front. in Nutrition

DOI 10.3389/fnut.2022.951000

Glyphosate and its formulations Roundup Bioflow and RangerPro alter bacterial and fungal community composition in the rat caecum microbiome

Mesnage R, Panzacchi P, Bourne E, Mein CA, Perry M, Hu J, Chen J, Mandrioli D, Belpoggi F, Antoniou MN (2022)

Front. Microbiol. 13:888853

DOI 10.3389/fmicb.2022.888853

Transcriptome analysis of human mammary epithelial cells treated with bisphenol A and bisphenol A analogue mixtures reveals major alterations in multiple cellular pathways

Mesnage R, Omriouate H, Antoniou MN (2022)

Public Health and Toxicology 2(4):17

DOI 10.18332/pht/155263

Molecular toxicity study on glyphosate, Roundup MON 52276 and a low-dose pesticide mixture administered to adult Female rats for 90 days

Mesnage R, Antoniou MN (2022)

All Life 15:1, 1273-1275

DOI 10.1080/26895293.2022.2156626

The surfactant co-formulant POEA in the glyphosate-based herbicide RangerPro but not glyphosate alone causes necrosis in Caco-2 and HepG2 human cell lines and ER stress in the ToxTracker assay

Mesnage R, Ferguson S, Brandsma I, Moelijker N, Zhang G, Mazzacuva F, Caldwell A, Halket J, Antoniou MN (2022)

Food and Chemical Toxicology. Available online 24 August 2022, 113380

DOI 10.1016/j.fct.2022.113380

Glyphosate Exposure in Early Pregnancy and Reduced Fetal Growth: A Prospective Observational Study of High-Risk Pregnancies

Gerona RR, Reiter JL, Proctor C, Ying J, Antoniou M, Mesnage R, Winchester P (2022)

Environ Health 21, Article number: 95

DOI 10.1186/s12940-022-00906-3

Microbiome

Mesnage R (2022)

Reference Module in Biomedical Sciences 2022

DOI 10.1016/B978-0-12-824315-2.00085-3

Information Resources in Toxicology

Mesnage R, Buha A (2022)

Reference Module in Biomedical Sciences 2022

DOI 10.1016/B978-0-12-824315-2.00082-8

Alterations in infant gut microbiome composition and metabolism after exposure to glyphosate and Roundup and/or a spore-based formulation using the SHIME® technology

Mesnage R, Calatayud M, Duysburgh C, Marzorati M, Antoniou M (2022)

Gut Microbiome, 1-30

DOI 10.1017/gmb.2022.5

Impacts of dietary exposure to pesticides on faecal microbiome metabolism in adult twins

Mesnage R, Bowyer R, El Balkhi S, Saint-Marcoux F, Gardere A, Ducarmon QR, Geelen AR, Zwittink RD, Tsoukalas D, Sarandi E, Paramera EI, Spector T, Steves CJ, Antoniou MN (2022)

Environ Health 21, 46

DOI 10.1186/s12940-022-00860-0

Estimation of Redox Status in Military Pilots during Hypoxic Flight-Simulation Conditions—A Pilot Study

Petraki K, Grammatikopoulou MG, Tekos F, Skaperda Z, Orfanou M, Mesnage R, BVassilakou T, Kouretas D (2022)

Antioxidants. 2022; 11(7):1241

DOI 10.3390/antiox11071241

Clinical and Dietary Determinants of Ketosis During Long-Term Fasting in 1610 Subjects

Mesnage R, Grundler F, Ruppert PMM, Wilhelmi de Toledo F(2022)

Current Developments in Nutrition 6 (Supplement_1), 382-382

DOI 10.1093/cdn/nzac054.037

Leveraging artificial intelligence to advance the understanding of chemical neurotoxicity

Aschner M, Mesnage R, Docea AO, Paoliello MMB, Tsatsakis A, Giannakakis G, Papadakis GZ, Vinceti SR, Santamaria A, Skalny AV, Tinkov AA (2022)

NeuroToxicology 89:9-11

DOI 10.1016/j.neuro.2021.12.007

Comparative toxicogenomics of glyphosate and Roundup herbicides by mammalian stem cell-based genotoxicity assays and molecular profiling in Sprague-Dawley rats

Mesnage R, Mandrioli D, Falcioni L, Belpoggi F, Brandsma I, Bourne B, Savage E, Mein CA, Antoniou MN (2022)

Toxicological Sciences. Volume 186, Issue 1, Pages 83–101

DOI 10.1093/toxsci/kfab143

Improving pesticide-use data for the EU

Mesnage R, Straw EA, Benbrook C, Brown MJF, Chauzat M, Finger R, Goulson D, Leadbeater E, López-Ballesteros A, Möhring N, Neumann P, Stanley D, Stout JC, Thompson L, Topping CJ, White B, Zaller JG, Zioga E (2021)

Nature Ecology and Evolution. Published: 14/10/2021

DOI 10.1038/s41559-021-01574-1

Chronic effects of wild blueberry (poly) phenols on cognitive function in healthy older individuals: the BluFlow study

Hein S, Wood E, Fernandes F, Mesnage R, Rodriguez-Mateos A, Williams C (2021)

Proceedings of the Nutrition Society 80 (OCE2)

DOI 10.1017/S0029665121000811

Effects of Daily Wild Blueberry Consumption on Cognitive and Vascular Function in Healthy Older Individuals: A Randomized Double Blind Controlled Trial (the Bluflow Study)

Hein S, Wood E, Abhayaratne N, Mesnage R, Fernandes F, Williams C, Rodriguez-Mateos A (2021)

Current Developments in Nutrition, Volume 5, Issue Supplement_2, Page 318

DOI 10.1093/cdn/nzab037_0281

Genotoxicity evaluation of 2,4-D, dicamba and glyphosate alone or in combination with cell reporter assays for DNA damage, oxidative stress and unfolded protein response

Mesnage R, Brandsma B, Moelijker N, Zhang G, Antoniou MN (2021)

Food Chem Toxicol. 2021 Oct 6;157:112601

DOI 10.1016/j.fct.2021.112601

Alterations in small RNA profiles in liver following a subchronic exposure to a low-dose pesticide mixture in Sprague-Dawley rats

Mesnage R, Mahmud N, Mein CA, Antoniou MN (2021)

Toxicol Lett. 2021 Oct 6:S0378-4274(21)00848-1

DOI 10.1016/j.toxlet.2021.10.001

Excretion of heavy metals and glyphosate in urine and hair before and after long-term fasting in humans

Grundler F, Mesnage R, Séralini GE, Peynet V, Wilhelmi de Toledo F (2021)

Front. Nutr. 8:708069

DOI 10.3389/fnut.2021.708069

Commentary: Novel strategies and new tools to curtail the health effects of pesticides

Benbrook C, Perry MJ, Belpoggi F, Landrigan PJ, Perro M, Mandrioli D, Antoniou MN, Winchester P, Mesnage R (2021)

Environ Health 20, 87

DOI 10.1186/s12940-021-00773-4

Long-term fasting improves lipoprotein-associated atherogenic risk in humans

Grundler R, Plonné D, Mesnage R, Müller D, Sirtori CR, Ruscica M, Wilhelmi de Toledo F (2021)

European Journal of Nutrition

DOI 10.1007/s00394-021-02578-0

Multi-omics phenotyping of the gut-liver axis reveals metabolic perturbations from a low-dose pesticide mixture in Sprague-Dawley rats

Mesnage R, Teixeira M, Mandrioli D, Falcioni L, Ducarmon QR, Zwittink RD, Amiel C, Panoff J, Bourne B, Savage E, Mein CA, Belpoggi F, Antoniou MN (2021)

Communications Biology 4, 471

DOI 10.1038/s42003-021-01990-w

Use of shotgun metagenomics and metabolomics to evaluate the impact of glyphosate or Roundup MON 52276 on the gut microbiota and serum metabolome of Sprague-Dawley rats

Mesnage R, Teixeira M, Mandrioli D, Falcioni L, Ducarmon QR, Zwittink RD, Mazzacuva F, Caldwell A, Halket J, Amiel C, Panoff J, Belpoggi F, Antoniou MN (2021)

Environmental Health Perspectives. Jan;129(1):17005

DOI 10.1289/EHP6990

Analytical strategies to study the gut microbiome in toxicology

Mesnage R and Antoniou MN (2021)

In Tsatsakis A ed. Toxicological Risk Assessment and Multi-System Health Impacts from Exposure. Elsevier

DOI 10.1016/B978-0-323-85215-9.00032-5

Redox Biomarker Baseline Levels in Cattle Tissues and Their Association with Meat Quality

Skaperda Z, Argyriadou A, Nechalioti P, Alvanou M, Makria S, Bouroutzika E, Kyriazis ID, Tekos F, Veskoukis AS, Kallitsis T, Mesnage R, Arsenos G, Kouretas D (2021)

Antioxidants. 10(6), 958

DOI 10.3390/antiox10060958

Urinary excretion of herbicide co-formulants after oral exposure to Roundup MON 52276 in rats

Mesnage R, Mazzacuva F, Caldwell A, Halket J, Antoniou MN (2021)

Environmental Research. Available online 1 April 2021

DOI 10.1016/j.envres.2021.111103

Impacts of a glyphosate-based herbicide on the gut microbiome of three earthworm species (Alma millsoni, Eudrilus eugeniae and Libyodrilus violaceus): a pilot study

Owagboriaye F, Mesnage R, Dedeke G, Adegboyega T, Aladesida A, Adeleke M, Owa S, Antoniou MN (2021)

Toxicology Reports. Available online 31 March 2021

DOI 10.1016/j.toxrep.2021.03.021

Herbicides: Chemistry, Efficacy, Toxicology, and Environmental Impacts

Mesnage R, Zaller JG (2021)

Emerging Issues in Analytical Chemistry. Cambridge, MA: Elsevier in cooperation with RTI Press

DOI 10.1016/B978-0-12-823674-1

Herbicides: Brief history, agricultural use, and potential alternatives for weed control

Mesnage R, Székács A, Zaller JG (2021)