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Robin Mesnage

Publications

2024

Wilhelmi de Toledo F, Grundler F, Mesnage R (2024). World’s longest medically documented repeated fasting history in a 92 years old man who fasted 21 days yearly for 45 years: a case report. Journal of Integrative and Complementary Medicine. DOI 10.1089/jicm.2023.0352
Hu J, Mesnage R, Tuohy K, Heiss C, Rodriguez-Mateos A (2024). (Poly)phenol-related gut metabotypes and human health: an update Food and Function DOI 10.1039/D3FO04338J
Klátyik S, Simon G, Oláh M, Takács E,Mesnage R, Antoniou MN, Zaller J, Székács A (2024). Aquatic ecotoxicity of glyphosate, its formulations, and co-formulants: evidence from 2010 to 2023 Environmental Sciences Europe 36:22 DOI 10.1186/s12302-024-00849-1

2023

Grundler F,Mesnage R, Cerrada A, Wilhelmi de Toledo F (2023) Improvements during long-term fasting in patients with long COVID a case series and literature review Front. Nutr. Sec. Clinical Nutrition. Volume 10 - 2023. DOI 10.3389/fnut.2023.1195270
Law PP, Rodriguez-Algarra F, Asenius F, Gregori M, Seaborne R, Yildizoglu S, Miller J, Mesnage R, Antoniou MN, Li W, Tan Q, Hillman SL, Rakyan V, Williams DJ, Holland ML (2023) Ribosomal DNA copy number is associated with body mass in humans and other mammals bioRxiv 2023.08.03.551775; DOI 10.1101/2023.08.03.551775
Ducarmon Q, Grundler F, Le Maho Y, Wilhelmi de Toledo F, Zeller G, Habold C, Mesnage R(2023) Remodelling of the intestinal ecosystem during caloric restriction and fasting. Trends in Microbiology. DOI 10.1016/j.tim.2023.02.009
Wood E, Hein S, Mesnage R, Fernandes F, Abhayaratne N, Xu Y, Zhang Z, Bell L, Williams C, Rodriguez-Mateos A (2023) Wild Blueberry (Poly)phenols can Improve Vascular Function And Cognitive Performance In Healthy Older Males And Females: A Double-Blind Randomized Controlled Trial The American Journal of Clinical Nutrition. DOI 10.1016/j.ajcnut.2023.03.017
Docea A, Cirstea AE, Cercelaru L, Drocas AI, Dinca V, Mesnage R, Marginean C, Radu A, Popa DG, Rogoveanu O, Mitrut R, Antoniou MN, Tsatsakis A, Hernández AF, Calina D (2023) Effect of perinatal exposure to glyphosate and its mixture with 2,4-D and dicamba on rat dam kidney and thyroid function and offspring's health. Environmental Research. Available online 17 August 2023, 116908 DOI: 10.1016/j.envres.2023.116908.
Straw EA, Mesnage R, Brown MF, Antoniou MN (2023) No impacts of glyphosate or Crithidia bombi, or their combination, on the bumblebee microbiome. Scientific Reports. DOI: 10.1038/s41598-023-35304-3.
Klátyik S, Simon G, Oláh M, Mesnage R, et al., (2023) Terrestrial ecotoxicity of glyphosate, its formulations, and co-formulants: evidence from 2010–2023. Environ Sci Eur 35, 51. DOI: 10.1186/s12302-023-00758-9.
Nechalioti P, Karampatzakis T, Mesnage R, Antoniou MN, Ibragim M, Tsatsakis A, Docea A, Nepka C, Kouretas D (2023) Evaluation of perinatal exposure of glyphosate and its mixture with 2,4-D and dicamba οn liver redox status in Wistar rats. Environmental Research 228: 115906. DOI 10.1016/j.envres.2023.115906
Mesnage R, Omriouate H, Antoniou MN (2023) Comparison of transcriptome alterations induced by pendimethalin or its commercial formulation Stomp Aqua in human MCF-7, MCF-10A and MCF-12A mammary epithelial cells BMC Research Notes 16, 62. DOI 10.1186/s13104-023-06327-w
Mesnage R, Grundler F, Wilhelmi de Toledo F (2023) Leveraging the self-healing abilities of our body to promote healthy longevity. Public Health Toxicology 3(1). DOI 10.18332/pht/161464
Mesnage R, Nepka C, Ferguson S, Kouretas D, Stivaktakis PD, Calina D, Tsatsakis A, Antoniou MN, Docea A (2023) The GlyphoMix protocol: Multiorgan changes caused by prenatal exposure to glyphosate or its mixture with 2,4-D and dicamba in rats Public Health Toxicology. 3(1):7 DOI 10.18332/pht/161987
Celebi O, Taghizadehghalehjoughi A, Celebi D, Mesnage R, Golokhvas KS, Arsene AL, Spandidos DA, Tsatsakis A (2023). Effect of Combination of Lactobacillus acidophilus (Probiotic) with Vitamin K3 and Vitamin E on Escherichia coli and Staphylococcus aureus: in vitro pathogen model. Molecular Medicine Reports 27: 119. DOI 10.3892/mmr.2023.13006
Powell C, Mesnage R, Antoniou MN, Vandenberg LN (2023).Low-Dose Effects of Environmental Chemicals: Bisphenol A as a Case Study. Reference Module in Biomedical Sciences. Encyclopedia of Toxicology, 4th Edition. DOI 10.1016/B978-0-12-824315-2.00762-4
Benbrook C, Mesnage R, Sawyer W. (2023) Genotoxicity Assays Published since 2016 Shed New Light on the Oncogenic Potential of Glyphosate-Based Herbicides. Agrochemicals. 2(1):47-68. DOI 10.3390/agrochemicals2010005
Sevim Ç, Akpınar E, Aksu EH, Ömür AD, Yıldırım S, Kara M, Bolat İ, Tsatsakis A, Mesnage R, Golokhvast KS, Uzunçakmak SK, Ersoylu RN (2023) Reproductive Effects of S. boulardii on Sub-Chronic Acetamiprid and Imidacloprid Toxicity in Male Rats. Toxics. 11(2):170. DOI 10.3390/toxics11020170
Mesnage R, Benbrook C (2023). Use of the concept “environmentally relevant level” in linking the results of pesticide toxicity studies to public health outcomes All Life. 16:1 DOI 10.1080/26895293.2023.2167872

2022

Ferguson S, Mesnage R, Antoniou M (2022). Cytotoxicity mechanisms of eight major herbicide active ingredients in comparison to their commercial formulations Toxics. 10(11), 711. DOI 2305-6304/10/11/711
Grundler F, Viallon M, Mesnage R, Ruscica M, von Schacky C, Madeo F, Hofer S, Mitchell S, Croisille P and Wilhelmi de Toledo F. (2022). Long-term fasting: multi-system adaptations in humans (GENESIS) study - a single-arm interventional trial Front. in Nutrition DOI 10.3389/fnut.2022.951000
Mesnage R, Panzacchi P, Bourne E, Mein CA, Perry M, Hu J, Chen J, Mandrioli D, Belpoggi F, Antoniou MN (2022). Glyphosate and its formulations Roundup Bioflow and RangerPro alter bacterial and fungal community composition in the rat caecum microbiome Front. Microbiol. 13:888853 DOI 10.3389/fmicb.2022.888853
Mesnage R, Omriouate H, Antoniou MN. Transcriptome analysis of human mammary epithelial cells treated with bisphenol A and bisphenol A analogue mixtures reveals major alterations in multiple cellular pathways. Public Health and Toxicology. 2(4):17. DOI 10.18332/pht/155263
Mesnage R, Antoniou MN (2022). Molecular toxicity study on glyphosate, Roundup MON 52276 and a low-dose pesticide mixture administered to adult Female rats for 90 days. All Life. 15:1, 1273-1275. DOI 10.1080/26895293.2022.2156626
Mesnage R, Ferguson S, Brandsma I, Moelijker N, Zhang G, Mazzacuva F, Caldwell A, Halket J, Antoniou MN (2022). The surfactant co-formulant POEA in the glyphosate-based herbicide RangerPro but not glyphosate alone causes necrosis in Caco-2 and HepG2 human cell lines and ER stress in the ToxTracker assay Food and Chemical Toxicology. Available online 24 August 2022, 113380. DOI 10.1016/j.fct.2022.113380
Gerona RR, Reiter JL, Proctor C, Ying J, Antoniou M, Mesnage R, Winchester P (2022). Glyphosate Exposure in Early Pregnancy and Reduced Fetal Growth: A Prospective Observational Study of High-Risk Pregnancies. Environ Health 21, Article number: 95 DOI 10.1186/s12940-022-00906-3
Mesnage R (2022). Microbiome. Reference Module in Biomedical Sciences 2022. DOI 10.1016/B978-0-12-824315-2.00085-3
Mesnage R, Buha A (2022). Information Resources in Toxicology. Reference Module in Biomedical Sciences 2022. DOI 10.1016/B978-0-12-824315-2.00082-8
Mesnage R, Calatayud M, Duysburgh C, Marzorati M, Antoniou M (2022). Alterations in infant gut microbiome composition and metabolism after exposure to glyphosate and Roundup and/or a spore-based formulation using the SHIME® technology. Gut Microbiome, 1-30. doi: doi:10.1017/gmb.2022.5
Mesnage R, Bowyer R, El Balkhi S, Saint-Marcoux F, Gardere A, Ducarmon QR, Geelen AR, Zwittink RD,Tsoukalas D, Sarandi E, Paramera EI, Spector T, Steves CJ, Antoniou MN (2022). Impacts of dietary exposure to pesticides on faecal microbiome metabolism in adult twins Environ Health 21, 46. doi: 10.1186/s12940-022-00860-0
Petraki K, Grammatikopoulou MG, Tekos F, Skaperda Z, Orfanou M, Mesnage R, BVassilakou T, Kouretas D. Estimation of Redox Status in Military Pilots during Hypoxic Flight-Simulation Conditions—A Pilot Study. Antioxidants. 2022; 11(7):1241. doi: 10.3390/antiox11071241
Mesnage R, Grundler F, Ruppert PMM, Wilhelmi de Toledo F(2022). Clinical and Dietary Determinants of Ketosis During Long-Term Fasting in 1610 Subjects. Current Developments in Nutrition 6 (Supplement_1), 382-382 doi: 10.1093/cdn/nzac054.037
Aschner M, Mesnage R, Docea AO, Paoliello MMB, Tsatsakis A, Giannakakis G, Papadakis GZ, Vinceti SR, Santamaria A, Skalny AV, Tinkov AA (2022) Leveraging artificial intelligence to advance the understanding of chemical neurotoxicity. NeuroToxicology 89:9-11. DOI 10.1016/j.neuro.2021.12.007
Mesnage R, Mandrioli D, Falcioni L, Belpoggi F, Brandsma I, Bourne B, Savage E, Mein CA, Antoniou MN (2022). Comparative toxicogenomics of glyphosate and Roundup herbicides by mammalian stem cell-based genotoxicity assays and molecular profiling in Sprague-Dawley rats. Toxicological Sciences. Volume 186, Issue 1, Pages 83–101. DOI 10.1093/toxsci/kfab143

2021

Mesnage R, Straw EA, Benbrook C, Brown MJF, Chauzat M, Finger R, Goulson D, Leadbeater E, López-Ballesteros A, Möhring N, Neumann P, Stanley D, Stout JC, Thompson L, Topping CJ, White B, Zaller JG and Zioga E (2021). Improving pesticide-use data for the EU. Nature Ecology and Evolution. Published: 14/10/2021doi: 10.1038/s41559-021-01574-1
Hein S, Wood E, Fernandes F, Mesnage R, Rodriguez-Mateos A, Williams C (2021). Chronic effects of wild blueberry (poly) phenols on cognitive function in healthy older individuals: the BluFlow study Proceedings of the Nutrition Society 80 (OCE2). doi: 10.1017/S0029665121000811
Hein S, Wood E, Abhayaratne N, Mesnage R, Fernandes F, Williams C, Rodriguez-Mateos A (2021). Effects of Daily Wild Blueberry Consumption on Cognitive and Vascular Function in Healthy Older Individuals: A Randomized Double Blind Controlled Trial (the Bluflow Study). Current Developments in Nutrition, Volume 5, Issue Supplement_2, Page 318 doi: 10.1093/cdn/nzab037_0281
Mesnage R, Brandsma B, Moelijker N, Zhang G, Antoniou MN (2021). Genotoxicity evaluation of 2,4-D, dicamba and glyphosate alone or in combination with cell reporter assays for DNA damage, oxidative stress and unfolded protein response Food Chem Toxicol. 2021 Oct 6;157:112601 doi: 10.1016/j.fct.2021.112601
Mesnage R, Mahmud N, Mein CA, Antoniou MN (2021). Alterations in small RNA profiles in liver following a subchronic exposure to a low-dose pesticide mixture in Sprague-Dawley rats Toxicol Lett. 2021 Oct 6:S0378-4274(21)00848-1 doi: 10.1016/j.toxlet.2021.10.001
Grundler F, Mesnage R, Séralini GE, Peynet V, Wilhelmi de Toledo F (2021). Excretion of heavy metals and glyphosate in urine and hair before and after long-term fasting in humans. Front. Nutr. 8:708069. doi: 10.3389/fnut.2021.708069
Benbrook C, Perry MJ, Belpoggi F, Landrigan PJ, Perro M, Mandrioli D, Antoniou MN, Winchester P, Mesnage R (2021). Commentary: Novel strategies and new tools to curtail the health effects of pesticides Environ Health 20, 87 doi: 10.1186/s12940-021-00773-4
Grundler R, Plonné D, Mesnage R, Müller D, Sirtori CR, Ruscica M, Wilhelmi de Toledo F (2021). Long-term fasting improves lipoprotein-associated atherogenic risk in humans. European Journal of Nutrition. DOI 10.1007/s00394-021-02578-0
Mesnage R, Teixeira M, Mandrioli D, Falcioni L, Ducarmon QR, Zwittink RD, Amiel C, Panoff J, Bourne B, Savage E, Mein CA, Belpoggi F, Antoniou MN (2021). Multi-omics phenotyping of the gut-liver axis reveals metabolic perturbations from a low-dose pesticide mixture in Sprague-Dawley rats. Communications Biology. 4, 471. DOI 10.1038/s42003-021-01990-w.
Mesnage R, Teixeira M, Mandrioli D, Falcioni L, Ducarmon QR, Zwittink RD, Mazzacuva F, Caldwell A, Halket J, Amiel C, Panoff J, Belpoggi F, Antoniou MN (2021). Use of shotgun metagenomics and metabolomics to evaluate the impact of glyphosate or Roundup MON 52276 on the gut microbiota and serum metabolome of Sprague-Dawley rats. Environmental Health Perspectives. Jan;129(1):17005 DOI 10.1289/EHP6990.
Mesnage R and Antoniou MN. Chapter Eight - Analytical strategies to study the gut microbiome in toxicology. In Tsatsakis A ed. Toxicological Risk Assessment and Multi-System Health Impacts from Exposure. Elsevier. DOI 10.1016/B978-0-323-85215-9.00032-5.
Skaperda Z, Argyriadou A, Nechalioti P, Alvanou M, Makria S, Bouroutzika E, Kyriazis ID, Tekos F, Veskoukis AS, Kallitsis T, Mesnage R, Arsenos G, Kouretas D (2021). Redox Biomarker Baseline Levels in Cattle Tissues and Their Association with Meat Quality. Antioxidants. 10(6), 958. 10.3390/antiox10060958
Mesnage R, Mazzacuva F, Caldwell A, Halket J, Antoniou MN (2021). Urinary excretion of herbicide co-formulants after oral exposure to Roundup MON 52276 in rats. Environmental Research. Available online 1 April 2021. 10.1016/j.envres.2021.111103
Owagboriaye F, Mesnage R, Dedeke G, Adegboyega T, Aladesida A, Adeleke M, Owa S Antoniou MN (2021).Impacts of a glyphosate-based herbicide on the gut microbiome of three earthworm species (Alma millsoni, Eudrilus eugeniae and Libyodrilus violaceus): a pilot study. Toxicology Reports. Available online 31 March 2021. DOI 10.1016/j.toxrep.2021.03.021.
Mesnage R, Zaller JG, eds. Herbicides: Chemistry, Efficacy, Toxicology, and Environmental Impacts. Emerging Issues in Analytical Chemistry. Cambridge, MA: Elsevier in cooperation with RTI Press. doi: https://www.elsevier.com/books/herbicides/mesnage/978-0-12-823674-1
  • Mesnage R, Székács A, and Zaller JG. Chapter One - Herbicides: Brief history, agricultural use, and potential alternatives for weed control. In Mesnage R, Zaller JG, eds. Herbicides: Chemistry, Efficacy, Toxicology, and Environmental Impacts. Elsevier in cooperation with RTI Press.
  • Mesnage R. Chapter Four - Co-formulants in commercial herbicides. In Mesnage R, Zaller JG, eds. Herbicides: Chemistry, Efficacy, Toxicology, and Environmental Impacts. Elsevier in cooperation with RTI Press.
  • Mesnage R and Antoniou MN. Chapter Six - Human health effects of herbicides used in intensive GM crop farming. In Mesnage R, Zaller JG, eds. Herbicides: Chemistry, Efficacy, Toxicology, and Environmental Impacts. Elsevier in cooperation with RTI Press.
  • Mesnage R. Chapter Nine - Analytical strategies to measure health effects of herbicides: predictive toxicology. In Mesnage R, Zaller JG, eds. Herbicides: Chemistry, Efficacy, Toxicology, and Environmental Impacts. Elsevier in cooperation with RTI Press.
  • Mesnage R and Zaller JG. Chapter Eleven - Herbicides: a necessary evil? An integrative overview. In Mesnage R, Zaller JG, eds. Herbicides: Chemistry, Efficacy, Toxicology, and Environmental Impacts. Elsevier in cooperation with RTI Press.

2020

Grundler F, Mesnage R, Michaelsen A, Wilhelmi de Toledo F (2020). Blood pressure changes in 1610 subjects with and without antihypertensive medication during long-term fasting. Journal of the American Heart Association. Published 23 Nov 2020. doi: 10.1161/JAHA.120.018649
Grundler F, Mesnage R, Goutzourelas N, Tekos F, Makri S, Brack M, Kouretas D, Wilhelmi de Toledo F (2020) Interplay between oxidative damage, the redox status, and metabolic biomarkers during long-term fasting. Food and Chemical Toxicology. https://doi.org/10.1016/j.fct.2020.111701
Wilhelmi de Toledo F, Grundler F, Goutzourelas N, Tekos F, Vassi E, Mesnage R, Kouretas D (2020) Influence of Long-Term Fasting on Blood Redox Status in Humans Antioxidants. 9(6), 496. https://doi.org/10.3390/antiox9060496
Mesnage R, Antoniou M (2020) Computational modelling provides insight into the effects of glyphosate on the shikimate pathway in the human gut microbiome. Current Research in Toxicology DOI: https://doi.org/10.1016/j.crtox.2020.04.001
Robinson C, Portier CJ, Čavoski A, Mesnage R, Roger A, Clausing P, Whaley P, Muilerman H, Lyssimachou A (2020) Achieving a High Level of Protection from Pesticides in Europe: Problems with the Current Risk Assessment Procedure and Solutions. European Journal of Risk Regulation, 1-31. DOI: https://doi.org/10.1017/err.2020.18
Marginǎ D, Ungurianu A, Purdel C, Tsoukalas D, Sarandi A, Thanasoula M, Tekos F, Kouretas D, Mesnage R, Tsatsakis A (2020) Chronic inflammation in the context of everyday life - dietary changes as mitigating factors. International Journal of Environmental Research and Public Health. Article 814023 DOI: 10.3390/ijerph17114135
Mesnage R, Oestreicher N, Poirier F, Nicolas V, Boursier C, Vélot C. (2020) Transcriptome profiling of the fungus Aspergillus nidulans exposed to a commercial glyphosate-based herbicide under conditions of apparent herbicide tolerance. Environmental Research. Available online 7 January 2020, 109116. DOI: https://doi.org/10.1016/j.envres.2020.109116
Mesnage R, Tsakiris IN, Antoniou MN, Tsakiris A (2020) Limitations in the evidential basis supporting health benefits from a decreased exposure to pesticides through organic food consumption. Current Opinion in Toxicology. DOI: https://doi.org/10.1016/j.cotox.2019.11.003

2019

Mesnage R, Grundler F, Schwiertz A, Le Maho Y, Wilhelmi de Toledo F. (2019) Changes in Human Gut Microbiota Composition Are Linked to the Energy Metabolic Switch During Ten Days of Fasting. Journal of Nutritional Science 8. DOI: https://doi.org/10.1017/jns.2019.33
Biserni M, Mesnage R, Wozniak E, Xenakis T, Mein CA, Antoniou MN (2019) Quizalofop-p-ethyl induces adipogenesis in 3T3-L1 adipocytes. Toxicological Sciences, kfz097, DOI: https://doi.org/10.1093/toxsci/kfz097
Tsiaoussis J., Antoniou MN, Koliarakis I, Mesnage R, Vardavas CI, Izotov BN., Psaroulaki A,, Tsatsakis AM (2019) Effects of single and combined toxic exposures on the gut microbiome: current knowledge and future directions. Toxicology Letters. Accepted 11 Apr 2019. DOI: https://doi.org/10.1016/j.toxlet.2019.04.014
Mesnage R, Le Roy C, Biserni M, Salles B, Antoniou MN. (2019) Relationship between faecal microbiota and plasma metabolome in rats fed NK603 and MON810 GM maize from the GMO90+ study. Food Chem Toxicol. 2019 Jun 3;131:110547 DOI: 10.1016/j.fct.2019.05.055
Mesnage R, Benbrook C, Antoniou MN. (2019). Insight into the confusion over surfactant co-formulants in glyphosate-based herbicides. Food Chem Toxicol. DOI: doi.org/10.1016/j.fct.2019.03.053
Mesnage R, Antoniou MN, Tsoukalas D, Goulielmos GN, Tsatsakis AM (2019). Gut microbiome metagenomics to understand how xenobiotics impact human health. Current Opinion in Toxicology.11-12:51–58. DOI: https://doi.org/10.1016/j.cotox.2019.02.002
Margina D, Mihai G, Ungurianu A, Mesnage R, Goumenou M, Sarigiannis DA, Aschner M, Spandidos DA, Renieri EA, Hernández AF, Tsatsakis A (2019) Overview of the effects of chemical mixtures with endocrine disrupting activity in the context of real‑life risk simulation (RLRS): An integrative approach. World Academy of Sciences Journal. DOI: 10.3892/wasj.2019.17
Antoniou MN, Nicolas A, Mesnage R, Biserni M, Rao FV, Vasquez Martin C (2019) Glyphosate does not substitute for glycine in proteins of actively dividing mammalian cells. BMC Research Notes. volume 12, Article number: 494. DOI: 10.1186/s13104-019-4534-3

2018

Nawaz MA, Mesnage R,Tsatsakis AM, Golokhvast KS, Yang SH, Antoniou MN, Chung G. Addressing concerns over the fate of DNA derived from genetically modified food in the human body: A review. Food Chem Toxicol. 2018 Dec 21;124:423-430. DOI: 10.1016/j.fct.2018.12.030
Sevim Ç, Çomaklı S, Taghizadehghalehjoughi A, Özkaraca M, Mesnage R, Kovatsi L, Burykina TI, Kalogeraki A, Antoniou MN, Tsatsakis A. An imazamox-based herbicide causes apoptotic changes in rat liver and pancreas. Toxicol Rep. 2018 Nov 19;6:42-50.DOI: 10.1016/j.toxrep.2018.11.008
Mesnage R, Séralini GE. (2018) Multidisciplinary approaches to evaluate pesticide effects on health and environment. Frontiers in Public Health 6, 268. DOI: https://doi.org/10.3389/fpubh.2018.00268
Goulson et al., 232 signatories. Call to restrict neonicotinoids. Science, 360(6392), 973.1–973. DOI: doi:10.1126/science.aau0432
Mesnage R, Biserni M, Wozniak E, Xenakis T, Mein CA, Antoniou MN (2018) Comparison of transcriptome responses to glyphosate, isoxaflutole, quizalofop-p-ethyl and mesotrione in the HepaRG cell line. Toxicology reports 5, 819-826.DOI: 10.1016/j.toxrep.2018.08.005
Mesnage R, Biserni M, Genkova D, Wesolowski L, Antoniou MN (2018) Evaluation of neonicotinoid insecticides for oestrogenic, thyroidogenic and adipogenic activity reveals imidacloprid causes lipid accumulation. J Appl Toxicol. 1–9.DOI: 10.1002/jat.3651
Mesnage R, Biserni M, Balu S, Frainay C, Poupin N, Jourdan F, Wozniak E, Xenakis T, Mein CA, Antoniou MN (2018) Integrated transcriptomics and metabolomics reveal signatures of lipid metabolism dysregulation in HepaRG liver cells exposed to PCB 126. Archives of Toxicology, 1-15.DOI: 10.1007/s00204-018-2235-7
Mesnage R, Antoniou MN. (2018) Ignoring Adjuvant Toxicity Falsifies the Safety Profile of Commercial Pesticides. Front Public Health. 2018 Jan 22;5:361.DOI: 10.3389/fpubh.2017.00361

2017

Lozano VL, Defarge N, Rocque LM, Mesnage R, Hennequin D, Cassier R, de Vendômois JS, Panoff JM, Séralini GE, Amiel C. (2017) Sex-dependent impact of Roundup on the rat gut microbiome. Toxicol Rep. Dec 19;5:96-107. DOI: https://doi.org/10.1016/j.toxrep.2017.12.005
Mesnage R,Antoniou MN. (2017) Facts and Fallacies in the Debate on Glyphosate Toxicity. Front Public Health. Nov 24;5:316.DOI: 10.3389/fpubh.2017.00316
Poirier F, Boursier C, Mesnage R, Oestreicher N, Nicolas V, Vélot C. (2017) Proteomic analysis of the soil filamentous fungus Aspergillus nidulans exposed to a Roundup formulation at a dose causing no macroscopic effect: a functional study. Environ Sci Pollut Res Int. 2017 Nov;24(33):25933-25946. DOI: 10.1007/s11356-017-0217-6
Mesnage R, Phedonos A, Biserni M, Arno M, Balu S, Christopher Corton J, Ugarte R, Antoniou MN (2017) Evaluation of estrogen receptor alpha activation by glyphosate-based herbicide constituents. Food and Chemical Toxicology. DOI: 10.1016/j.fct.2017.07.025
Mesnage R, Antoniou MN (2017) Roundup Ready! Glyphosate and the Current Controversy Over the World’s Leading Herbicide. In book: Encyclopedia of the Anthropocene – Reference Module in Earth Systems and Environmental Sciences. DOI: DOI: 10.1016/B978-0-12-409548-9.09981-4
Vandenberg LN, Blumberg B, Antoniou MN, Benbrook CM, Carroll L, Colborn T, Everett LG, Hansen M, Landrigan PJ, Lanphear BP, Mesnage R,Vom Saal FS, Welshons WV, Myers JP. (2017) Is it time to reassess current safety standards for glyphosate-based herbicides? J Epidemiol Community Health. 71(6):613-618. DOI: http://dx.doi.org/10.1136/jech-2016-208463
Mesnage R, Phedonos A, Arno M, Balu S, Christopher Corton J, Antoniou MN (2017) Editor’s Highlight: Transcriptome profiling reveals bisphenol A alternatives activate estrogen receptor alpha in human breast cancer cells. Toxicol Sci. 2017 158(2):431-443.DOI: 10.1093/toxsci/kfx101
Mesnage R, Arno M, Séralini GE, Antoniou M. (2017) Transcriptome and metabolome analysis of liver and kidneys of rats chronically fed NK603 Roundup-tolerant genetically modified maize. Environmental Sciences Europe. 29:6.DOI: 10.1186/s12302-017-0105-1
Mesnage R, Renney G, Séralini GE, Ward M, Antoniou M. (2017) Multiomics reveal non-alcoholic fatty liver disease in rats following chronic exposure to an ultra-low dose of Roundup herbicide. Scientific Reports. 2017. 6, 39328.DOI: 10.1038/srep39328

2016

Mesnage R, Agapito-Tenfen S, Vilperte V, Renney G, Ward M, Séralini GE, Nodari N, Antoniou M. (2016) An integrated multi-omics analysis of the NK603 Roundup-tolerant GM maize reveals metabolism disturbances caused by the transformation process. Scientific Reports. 6, 37855. DOI: https://doi.org/10.1038/srep37855
Deloménie C., Grentzmann G., Oestreicher N., Mesnage R, Vélot C. (2016) Development and validation of a custom microarray for global transcriptome profiling of the fungus Aspergillus nidulans. Current Genetics. 62(4):897-910.DOI: 10.1007/s00294-016-0597-z
Defarge N., Takács E., Lozano V., Mesnage R, Spiroux De Vendômois J., Séralini GE., Székács A. (2016) Co-formulants in glyphosate-based herbicides disrupt aromatase activity in human cells below toxic levels. Int J Environ Res Public Health. 13(3). pii: E264. DOI: 10.3390/ijerph13030264
Myers JP, Antoniou MN, Blumberg B, Carroll L, Colborn T, Everett LG, Hansen M, Landrigan PJ, Lanphear BP, Mesnage R, Vendenberg LN, vom Saal FS, Welshons WV, Benbrook CM (2016). Concerns over use of glyphosate-based herbicides and risks associated with exposures: a consensus statement. Environ Health. 15:19.DOI: 10.1186/s12940-016-0117-0

2015

Mesnage R, Arno M, Costanzo M, Malatesta M, Séralini GE, Antoniou MN (2015). Transcriptome profile analysis reflects rat liver and kidney damage following chronic ultra-low dose Roundup exposure. Environ Health. 14(1):70. DOI: 10.1186/s12940-015-0056-1
Mesnage R, Defarge N, Spiroux de Vendômois J, Séralini GE (2015) Potential toxic effects of glyphosate and its commercial formulations below regulatory limits. Food Chem Toxicol. 84:133-53. DOI: 10.1016/j.fct.2015.08.012
Mesnage R, Defarge N, Rocque LM, Spiroux de Vendômois J, Séralini GE (2015) Laboratory Rodent Diets Contain Toxic Levels of Environmental Contaminants: Implications for Regulatory Tests. PLoS One. 10(7):e0128429. DOI: 10.1371/journal.pone.0128429

2014

Mesnage R, Defarge N., Spiroux de Vendômois J.and Séralini G.-E. (2014) Letter to the Editor regarding “Delaney et al., 2014”: Uncontrolled GMOs and their associated pesticides make the conclusions unreliable. Food Chem Toxicol. DOI: 10.1016/j.fct.2014.07.003
Mesnage R,Séralini G.E. (2014) The need of a closer look for pesticide toxicity during GMO assessment. Chapter 10 in Practical Food Safety: Contemporary Issues and Future Directions, First Edition. Edited by Rajeev Bhat and Vicente M. Gómez-López. John Wiley & Sons, Ltd. DOI: https://doi.org/10.1002/9781118474563.ch10
Séralini G.E., Mesnage R, Defarge N., and Spiroux de Vendômois J. (2014) Conflicts of interests, confidentiality and censorship in health risk assessment: The example of an herbicide and a GMO. Environmental Sciences Europe 26:14.DOI: 10.1186/s12302-014-0013-6
Séralini G.E., Clair E., Mesnage R, Gress S., Defarge N., Malatesta M., Hennequin D. and Spiroux de Vendômois J. (2014) Republished study: Long-term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Environmental Sciences Europe 26:13. DOI: 10.1186/s12302-014-0014-5
Séralini G.E., Mesnage R, Defarge N., and Spiroux de Vendômois J. (2014) Conclusiveness of toxicity data and double standards. Food Chem Toxicol. 69: 357–359. DOI: 10.1016/j.fct.2014.04.018
Mesnage R, Defarge N., Spiroux de Vendômois J.and Séralini G.-E. (2014) Major pesticides are more toxic to human cells than their declared active principles. BioMed Research International. Vol 2014, Article ID 179691. DOI: 10.1155/2014/179691

2013

Séralini G.E., Mesnage R, Defarge N., Gress S., Hennequin D., Clair E., Malatesta M., and Spiroux de Vendômois J. (2013) Answers to critics : Why there is a long term toxicity due to NK603 Roundup-tolerant genetically modified maize and to a Roundup herbicide. Food and Chemical Toxicology.53: 461-8. DOI: 10.1016/j.fct.2012.11.007
Mesnage R, Bernay B., Séralini G.E. (2013) Ethoxylated adjuvants of glyphosate-based herbicides are active principles of human cell toxicity. Toxicology 16; 313(2-3):122-8. DOI: 10.1016/j.tox.2012.09.006
Mesnage R, Clair E., Gress S., Then C., Szekacs A. and Séralini G.-E. (2013) Cytotoxicity on human cells of Cry1Ab and Cry1Ac Bt insecticidal toxins alone or with a glyphosate-based herbicide. Journal of Applied Toxicology 7:695-9.DOI: 10.1002/jat.2712
Mesnage R, Gress S., Defarge N., and Séralini G.-E. (2013) Human cell toxicity of pesticides associated to wide scale agricultural GMOs. Theorie in der Ökologie, 7:118-20.

2012

Clair E., Mesnage R, Travert C., Séralini G.E. (2012) A glyphosate-based herbicide induces necrosis and apoptosis in mature rat testicular cells in vitro, and testosterone decrease at lower levels. Toxicology in vitro. 26(2): 269-79.DOI: 10.1016/j.tiv.2011.12.009
Benachour N., Clair E., Mesnage R, Séralini G.-E. (2012) Endocrine Disruptors“New discoveries and possible progress of evaluation”. Chapter in “Advances in Medicine and Biology, Volume 29” Nova Science Publishers.

Mesnage R, Moesch C., Le Grand R., Lauthier G., Spiroux de vendômois J., Gress. S. and Séralini G.E (2012). Glyphosate exposure in a farmer’s family. Journal of Environmental Protection. 3(9): 1001-1003. DOI: 10.4236/jep.2012.39115

Defarge N., Mesnage R, Gress S., Séralini G.E. (2012) Letter to the editor: developmental and reproductive outcomes of roundup and glyphosate in humans and animals. J Toxicol Environ Health B Crit Rev. 15(7): 433-40. DOI: 10.1080/10937404.2012.736857

2011

Séralini G.-E., Mesnage R, Clair E., Gress S., Cellier D., Spiroux de Vendômois J.(2011) Genetically Modified Crops Safety Assessments: Present Limits and Possible Improvements. Environmental Sciences Europe 23:10 DOI: https://doi.org/10.1186/2190-4715-23-10
Gasnier C., Laurent C., Mesnage R, Clair E., Séralini G.E (2011) Defined plant extracts can protect human cells against combined xenobiotic effects. Journal of Occupational Medicine and Toxicology 6:3 .DOI: 10.1186/1745-6673-6-3

2010

Mesnage R, Clair E., Séralini G.-E. (2010) Roundup in Genetically modified crops: Regulation and toxicity in mammals. Theorie in der Ökologie 16:31-33
Séralini G.E., Spiroux de Vendomois J., Cellier D., Mesnage R, Clair E. (2010) Genetically modified crop consumption at large scale: Possible negative health impacts due to holes in assessment. Overview of the safety studies of GMOs performed on mammals. Theorie in der Ökologie 16:28-30
Clair E., Mesnage R, Gress S., Travert C., Séralini G.E. (2010) Un herbicide à base de glyphosate induit la nécrose et l’apoptose des cellules testiculaires de rats matures. Annales d’Endocrinologie 71 340–353
Mesnage R, Clair E., Spiroux de Vendômois J., Séralini G.E. (2010) Two cases of birth defects overlapping Stratton-Parker syndrome after multiple pesticide exposure. Occup Environ Med 67:359 .DOI: 10.1136/oem.2009.052969
Spiroux de Vendomois J., Cellier D., Vélot C., Clair E., Mesnage R, Séralini G.E. (2010) Debate on GMOs Health Risks After Statistical Findings in Regulatory Tests. Int. J. Biol. Sci. 6(6):590-598. 10.7150/ijbs.6.590
CONTACT: Robin Mesnage, Wilhelm-Beck-Str. 27, 88662 Überlingen, GERMANY.
EMAIL: robin.mesnage[at]buchinger-wilhelmi.com